Neonatal invasive candidiasis: A poorly understood entity

Evolving Invasive Neonatal Systemic Candidiasis, a Review

1Consultant Neonatologist, Neonatal Intensive Care Unit, Pediatric Department, Latifa Women & Children Hospital, Dubai Health Authority, UAE 2Consultant Neonatologist and Head of Pediatric Department & Neonatal Intensive Care Unit, Latifa Women & Children Hospital, Dubai Health Authority, UAE 3Specialist Senior Registrar, Neonatal Intensive Care Unit, Pediatric Department, Latifa Women & Childr...

Thrombosis – Besieged but Poorly Understood

In biology, thrombosis is a mechanism of maintaining the integrity of biological surfaces in higher mammals, limiting fluid loss, and facilitating the recognition, containment, and destruction of pathogens and foreign materials by a scaffold of fibrin and DNA strands. However, thrombosis may also lead to vascular occlusion and subsequent tissue damage. In medicine, thrombosis is a hallmark of l...

Invasive candidiasis and candidemia in pediatric and neonatal patients: A review of current guidelines

Several international and national guidelines have been proposed for the treatment and prevention of invasive candidiasis/candidemia (IC/C) in both neonatal and pediatric patients. This article is a review of the current guidelines, recommendations, and expert panel consensus of a number of associations and conferences on the prevention and management of IC and candidemia in both pediatric and ...

Premenstrual asthma: still poorly understood.

Nephrogenic ascites: a poorly understood syndrome.

Nephrogenic ascites is a condition characterized by the presence of massive ascites in a patient with ESRD. Neither the exact cause nor the pathogenesis of ascites formation is clearly understood. Patients frequently present with hypertension, moderate to massive ascites, minimal extremity edema, cachexia, and a history of dialysis-associated hypotension. The ascitic fluid is typically an exuda...